I have the weirdest computer problem! HELP!!!

[Deuce]

"When a rogue program decides to install its own version of system
fonts, it may replace the original version of the font file with a
shortcut in the font folder. Once this program is uninstalled, the
shortcut may now point to a font file that no longer exists. Windows
XP in turn reacts by turning all unspecified fonts into italics upon
next reboot.The simple way to fix this is to delete all shortcuts in
the font folder and replace them with the actual font file. By going
to
[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\WindowsNT\Cu rrentVersion\Fonts],
you can also double check the path of each font and look for any
suspicious paths."

quote from a google group http://groups.google.co.uk/group/mic...2a3aaa40f31ae3

that might point you in the right direction